Wouldn’t you like to know how medicine will work for you BEFORE it’s prescribed?
Whether you find yourself in the ER, preparing for a root canal, recovering from a heart attack or dealing with a cancer diagnosis, you want to know that the treatments you are receiving are working properly. Due to changes in DNA, many people will have a slower response or no response to specific medications, while others may experience increased side effects.
How Kailos can help you
Finding out during treatment or after the fact, that a certain medicine was not the right one can be avoided. Since everyone’s genes are different, knowing how you will respond to medicines in advance of treatment gives you and your physician the knowledge to prescribe treatment confidently. With Kailos’ PGxComplete report, you can work with your physician to select the right medicine and dosage combination for you based on your DNA, so that you get the desired effects of treatment ranging from pain relief, to cancer therapy. The Kailos test lets you know how you will respond to medication before you need it so you are informed and prepared.
Why would I respond differently?
There are many different types of genes in your DNA that control how your body uses medications. Kailos looks carefully at these genes to see how they can affect your treatment.
While some genes may affect a specific part of treatment, others may have broader impacts. For instance, the ‘CYP’ genes (i.e. CYP2D6, CYP2C19, CYP2C9, CYP3A4) are involved in how your body uses a majority of medications. However, CYP2D6 is involved in 25% of all medications. Additionally, a combination of these genes may cause different responses. This is the case with the cholesterol lowering medications (statins), where three genes (ABCB1, CYP3A5 & SLCO1B1) need to be combined to understand your response.
Some genes can impact how your body uses medicines in a good way by leading to better treatment response, a smaller required dosage and less cost for medication. However, some genes can cause negative reactions including harmful side effects or no effect at all. The good news is that alternate treatments are usually available. By understanding how your body uses medicines, you and your physician are able to immediately select the best treatment for your DNA.
Order the Kailos test today and get the most out of your treatment!
What is covered?
|Medicine classes||Generic medicine name|
|ADHD Medications||Amphetamine, Atomoxetine, Clonidine, Dexmethylphenidate, Dextroamphetamine, Lisdexamfetamine, Methylphenidate|
|Antiarrhythmics||Digoxin, Flecainide, Propafenone|
|Antidepressants||Amitriptyline, Citalopram, Clomipramine, Desipramine, Doxepin, Duloxetine, Escitalopram, Imipramine, Nortriptyline, Paroxetine, Sertraline, Trimipramine, Venlafaxine|
|Antiepileptics||Mephenytoin, Phenytoin, Valproic Acid|
|Antihypertensives||Atenolol, Benazepril, Enalapril, Imidapril, Irbesartan, Losartan, Metoprolol, Timolol, Verapamil|
|Antipsychotics||Aripiprazole, Clozapine, Haloperidol, Olanzapine, Risperidone|
|Chemotherapeutics||Capecitabine, Cisplatin, Cyclophosphamide, Fluorouracil, Leucovorin, Mercaptopurine, Methotrexate, Oxaliplatin, Paclitaxel, Tamoxifen, Tegafur, Thioguanine|
|General Anesthetics||Desflurane, Isoflurane, Nitrous Oxide, Sevoflurane, Succinylcholine|
|Hepatitis Antivirals||Peginterferon-alfa, Ribavirin|
|HIV/AIDS Antivirals||Efavirenz, Nelfinavir, Nevirapine|
|Immunosuppressants||Azathioprine, Cyclosporine, Sirolimus, Tacrolimus|
|Opioids||Codeine, Hydrocodone, Oxycodone, Tramadol|
|Platelet Aggregation Inhibitors||Clopidogrel|
|Proton Pump Inhibitors||Lansoprazole, Omeprazole, Pantoprazole|
|Statins||Atorvastatin, Fluvastatin, Lovastatin, Pravastatin, Rosuvastatin, Simvastatin|
|Thrombophilia||Risk factor for blood clot development|