KailosBlue is a highly secure, easily accessible cloud environment, for investigators to manage their NGS workflow, analyze sequences post-target enrichment and actively utilize their stored data. In combining the Amazon® cloud (secure & scalable), the industry leading alignment and genotyping systems (BWA & GATK), statistical resources and an intuitive user interface, investigators from any size lab can perform complex analysis of samples within a run and across multiple runs over time, independent of the sequencing equipment utilized.
KailosBlue provides an end-to-end informatics solution for targeted next-generation sequencing. The system can be used to plan and organize flowcells and configure sequencing runs. This feature is especially important for targeted sequencing approaches, such as Kailos Genetics’ TargetRich™ system, where dozens of samples are barcoded and pooled to efficiently and optimally utilize sequencer capacity. Raw data can be uploaded from sequencing instruments to the cloud for fast and secure alignment and analysis. Analysis, including variant identification, can be performed on DNA samples and compared against a reference sample (1000 Genomes, HapMap, User Defined) or across multiple samples run over any period of time, enabling entire studies to be compiled and analyzed in one system. KailosBlue cloud-based bioinformatics solution is compatible with data generated on the Illumina MiSeq®, GAIIx® and the Ion Torrent PGM®.